GRN, granulin precursor, 2896

N. diseases: 412; N. variants: 66
Source: ALL
Variant Gene Disease Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs1567886445
rs1567886445
Entrez Id: 2896
Gene Symbol: GRN
GRN
CUI: C0338451
Disease:
Frontotemporal dementia 		TTGTGAAGACAGGGTGCACTGCTGTC 0.700 CausalMutation CLINVAR
dbSNP: rs1567886206
rs1567886206
Entrez Id: 2896
Gene Symbol: GRN
GRN
CUI: C0338451
Disease:
Frontotemporal dementia 		TA 0.700 CausalMutation CLINVAR
dbSNP: rs1567887015
rs1567887015
Entrez Id: 2896
Gene Symbol: GRN
GRN
CUI: C0338451
Disease:
Frontotemporal dementia 		TA 0.700 CausalMutation CLINVAR
dbSNP: rs1567887496
rs1567887496
Entrez Id: 2896
Gene Symbol: GRN
GRN
CUI: C1843792
Disease:
FRONTOTEMPORAL LOBAR DEGENERATION WITH TDP43 INCLUSIONS, GRN-RELATED 		T 0.700 CausalMutation CLINVAR
dbSNP: rs1567887496
rs1567887496
Entrez Id: 2896
Gene Symbol: GRN
GRN
CUI: C3539123
Disease:
CEROID LIPOFUSCINOSIS, NEURONAL, 11 		T 0.700 CausalMutation CLINVAR
dbSNP: rs5848
rs5848
Entrez Id: 2896;284069
Gene Symbol: GRN;FAM171A2
GRN;FAM171A2
CUI: C2985280
Disease:
Blood Protein Measurement 		T 0.700 GeneticVariation GWASCAT Genomic atlas of the human plasma proteome. 29875488 2018
dbSNP: rs63749801
rs63749801
Entrez Id: 2896
Gene Symbol: GRN
GRN
CUI: C1843792
Disease:
FRONTOTEMPORAL LOBAR DEGENERATION WITH TDP43 INCLUSIONS, GRN-RELATED 		T 0.700 CausalMutation CLINVAR
dbSNP: rs63749801
rs63749801
Entrez Id: 2896
Gene Symbol: GRN
GRN
CUI: C0338451
Disease:
Frontotemporal dementia 		T 0.700 CausalMutation CLINVAR
dbSNP: rs63750077
rs63750077
Entrez Id: 2896
Gene Symbol: GRN
GRN
CUI: C1843792
Disease:
FRONTOTEMPORAL LOBAR DEGENERATION WITH TDP43 INCLUSIONS, GRN-RELATED 		T 0.700 CausalMutation CLINVAR
dbSNP: rs63750411
rs63750411
Entrez Id: 2896
Gene Symbol: GRN
GRN
CUI: C1843792
Disease:
FRONTOTEMPORAL LOBAR DEGENERATION WITH TDP43 INCLUSIONS, GRN-RELATED 		T 0.700 CausalMutation CLINVAR
dbSNP: rs63751180
rs63751180
Entrez Id: 2896
Gene Symbol: GRN
GRN
CUI: C1843792
Disease:
FRONTOTEMPORAL LOBAR DEGENERATION WITH TDP43 INCLUSIONS, GRN-RELATED 		T 0.700 CausalMutation CLINVAR
dbSNP: rs63751294
rs63751294
Entrez Id: 2896
Gene Symbol: GRN
GRN
CUI: C1843792
Disease:
FRONTOTEMPORAL LOBAR DEGENERATION WITH TDP43 INCLUSIONS, GRN-RELATED 		T 0.700 CausalMutation CLINVAR
dbSNP: rs770058074
rs770058074
Entrez Id: 2896
Gene Symbol: GRN
GRN
CUI: C3539123
Disease:
CEROID LIPOFUSCINOSIS, NEURONAL, 11 		T 0.700 GeneticVariation CLINVAR
dbSNP: rs794729671
rs794729671
Entrez Id: 2896
Gene Symbol: GRN
GRN
CUI: C0338451
Disease:
Frontotemporal dementia 		GT 0.700 CausalMutation CLINVAR
dbSNP: rs606231220
rs606231220
Entrez Id: 2896
Gene Symbol: GRN
GRN
CUI: C1843792
Disease:
FRONTOTEMPORAL LOBAR DEGENERATION WITH TDP43 INCLUSIONS, GRN-RELATED 		GCTGC 0.700 CausalMutation CLINVAR
dbSNP: rs1392550887
rs1392550887
Entrez Id: 2896
Gene Symbol: GRN
GRN
CUI: C3539123
Disease:
CEROID LIPOFUSCINOSIS, NEURONAL, 11 		GC 0.700 CausalMutation CLINVAR
dbSNP: rs1392550887
rs1392550887
Entrez Id: 2896
Gene Symbol: GRN
GRN
CUI: C1843792
Disease:
FRONTOTEMPORAL LOBAR DEGENERATION WITH TDP43 INCLUSIONS, GRN-RELATED 		GC 0.700 CausalMutation CLINVAR
dbSNP: rs794729672
rs794729672
Entrez Id: 2896
Gene Symbol: GRN
GRN
CUI: C0338451
Disease:
Frontotemporal dementia 		GC 0.700 CausalMutation CLINVAR
dbSNP: rs1555611412
rs1555611412
Entrez Id: 2896
Gene Symbol: GRN
GRN
CUI: C1843792
Disease:
FRONTOTEMPORAL LOBAR DEGENERATION WITH TDP43 INCLUSIONS, GRN-RELATED 		G 0.700 CausalMutation CLINVAR Strikingly different clinicopathological phenotypes determined by progranulin-mutation dosage. 22608501 2012
dbSNP: rs1555611412
rs1555611412
Entrez Id: 2896
Gene Symbol: GRN
GRN
CUI: C3539123
Disease:
CEROID LIPOFUSCINOSIS, NEURONAL, 11 		G 0.700 CausalMutation CLINVAR Mutations in progranulin are a major cause of ubiquitin-positive frontotemporal lobar degeneration. 16950801 2006
dbSNP: rs1555611412
rs1555611412
Entrez Id: 2896
Gene Symbol: GRN
GRN
CUI: C3539123
Disease:
CEROID LIPOFUSCINOSIS, NEURONAL, 11 		G 0.700 CausalMutation CLINVAR Genetic and clinical features of progranulin-associated frontotemporal lobar degeneration. 21482928 2011
dbSNP: rs1555611412
rs1555611412
Entrez Id: 2896
Gene Symbol: GRN
GRN
CUI: C3539123
Disease:
CEROID LIPOFUSCINOSIS, NEURONAL, 11 		G 0.700 CausalMutation CLINVAR The spectrum of mutations in progranulin: a collaborative study screening 545 cases of neurodegeneration. 20142524 2010
dbSNP: rs1555611412
rs1555611412
Entrez Id: 2896
Gene Symbol: GRN
GRN
CUI: C3539123
Disease:
CEROID LIPOFUSCINOSIS, NEURONAL, 11 		G 0.700 CausalMutation CLINVAR Strikingly different clinicopathological phenotypes determined by progranulin-mutation dosage. 22608501 2012
dbSNP: rs1555611412
rs1555611412
Entrez Id: 2896
Gene Symbol: GRN
GRN
CUI: C1843792
Disease:
FRONTOTEMPORAL LOBAR DEGENERATION WITH TDP43 INCLUSIONS, GRN-RELATED 		G 0.700 CausalMutation CLINVAR The spectrum of mutations in progranulin: a collaborative study screening 545 cases of neurodegeneration. 20142524 2010
dbSNP: rs1555611412
rs1555611412
Entrez Id: 2896
Gene Symbol: GRN
GRN
CUI: C3539123
Disease:
CEROID LIPOFUSCINOSIS, NEURONAL, 11 		G 0.700 CausalMutation CLINVAR Mutations in progranulin cause tau-negative frontotemporal dementia linked to chromosome 17. 16862116 2006